A chemical reaction that involves six different atoms can be represented by the following equation:
A + B + C → D + E + F
In this reaction, there are six distinct atoms involved, represented by the symbols A, B, C, D, E, and F. Each of these atoms combines or rearranges to form new molecules or compounds represented by the symbols D, E, and F. The reaction could involve elements from various groups of the periodic table or even compounds with different functional groups. The specific reaction and the nature of the atoms involved would depend on the context and the elements or compounds used.