To prepare 400ml of a 50mg/ml solution using 500g of aspirin crystals, you'll need to perform some calculations and follow these steps:
Step 1: Calculate the total amount of aspirin needed. Since you want to prepare a 50mg/ml solution, and you need 400ml of that solution, the total amount of aspirin needed can be calculated as follows:
Total aspirin = Concentration (mg/ml) x Volume (ml) Total aspirin = 50mg/ml x 400ml Total aspirin = 20,000mg
Step 2: Convert the mass of aspirin from grams to milligrams. The given amount of aspirin is 500g, so you'll need to convert it to milligrams:
500g = 500,000mg
Step 3: Determine the volume of solvent needed. To prepare a 400ml solution, you'll need a solvent volume of 400ml.
Step 4: Prepare the solution. To prepare the solution, follow these steps:
a. Weigh 20,000mg (or 20g) of aspirin crystals. b. Add the aspirin crystals to a container. c. Add a small volume of solvent (e.g., water or an appropriate solvent) to dissolve the aspirin. Stir or swirl the container until the crystals are completely dissolved. d. Once the aspirin crystals have dissolved, add more solvent (water or an appropriate solvent) gradually while continuing to stir until the total volume reaches 400ml. e. Ensure that the solution is thoroughly mixed and homogeneous.
By following these steps, you will have prepared 400ml of a 50mg/ml aspirin solution using the given 500g of aspirin crystals.