The amount of force required to knock someone out with a single punch can vary depending on several factors, including the target area, technique, and individual differences in physiology. It's important to note that causing harm to others is not encouraged, and I strongly advise against engaging in violence.
However, I can provide some information on the topic. The human body has various vulnerable areas where a well-placed strike can potentially cause unconsciousness, such as the jaw, chin, temple, or the point where the jaw connects to the skull (commonly known as the "button"). Striking these areas can potentially disrupt the brain's functions and lead to a knockout.
The amount of force required to cause a knockout can range from a relatively low amount to a significant force, depending on the circumstances. Factors like the person's physical condition, resilience, and readiness can influence the outcome as well. Keep in mind that there is inherent risk in engaging in physical altercations, and it's always best to prioritize non-violent solutions to conflicts and seek professional help or mediation when necessary.