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According to the law of conservation of mass-energy, matter cannot be created or destroyed in isolated systems. This principle is a fundamental concept in physics, stemming from the conservation laws of energy and momentum. It states that the total mass-energy in a closed system remains constant over time.

In classical physics, where matter is treated as distinct particles, the conservation of mass is considered separately from the conservation of energy. However, in the context of relativity, mass and energy are two forms of the same underlying quantity, known as mass-energy. This is expressed by Einstein's famous equation, E = mc², where E represents energy, m represents mass, and c represents the speed of light.

In certain situations, matter can appear to be created or destroyed through processes involving energy conversion or particle interactions. These processes can involve particle-antiparticle annihilation, pair production, or nuclear reactions. However, in all these cases, the total mass-energy before and after the process remains conserved.

For instance, in particle-antiparticle annihilation, a particle and its corresponding antiparticle collide and their masses are converted into energy in the form of photons or other particles. While the particles themselves may no longer exist, the total mass-energy of the system remains unchanged.

Similarly, in pair production, energy can be transformed into mass as long as it is within the constraints of energy conservation. High-energy photons, for example, can spontaneously convert into an electron-positron pair when in the presence of another particle or a strong electromagnetic field.

Nuclear reactions, such as those occurring in stars or nuclear power plants, involve the conversion of nuclear mass into energy or vice versa. These reactions release or absorb energy by altering the binding energies of atomic nuclei. Again, the total mass-energy is conserved throughout these processes.

In summary, while matter can undergo transformations and convert into different forms of energy, the total mass-energy in a closed system remains constant. The principle of the conservation of mass-energy is a foundational concept in physics and holds true within the framework of our current understanding of the laws of nature.

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