A chemical reaction that involves 6 different atoms can be represented by the following equation:
A + B + C → D + E + F
In this example, A, B, and C represent three different atoms or molecules that react together, and D, E, and F represent the resulting atoms or molecules. The reaction involves a total of 6 different atoms. It's important to note that this is a simplified representation, and actual chemical reactions can involve many more atoms and molecules.