Yes, the Quran makes a reference to the Milky Way in a verse. In Surah Al-Burooj (Chapter 85), Verse 1, it states:
"By the sky containing great stars."
The Arabic term used in this verse is "burooj," which is translated as "great stars" or "fortified towers." Islamic scholars and commentators have interpreted this term to refer to celestial objects or groups of stars, including the Milky Way.
It's worth noting that the Quran uses poetic language and imagery to convey its messages, and its descriptions of natural phenomena are often metaphorical. The mention of the "sky containing great stars" can be understood as highlighting the awe-inspiring nature of the cosmos and the wonders of the universe, rather than providing a detailed scientific description of the Milky Way as we understand it in modern astronomy.