There is no historical record of a great worldwide famine occurring during the time of Emperor Claudius (41-54 AD). While famines and food shortages were not uncommon in the ancient world, there is no specific evidence to suggest a famine of global proportions taking place during Claudius' reign.
During the reign of Claudius, the Roman Empire faced some regional food shortages and famines, but these were localized events rather than a worldwide catastrophe. The empire took measures to address these issues by importing grain from other regions, particularly from Egypt, to mitigate the impact of scarcity in certain areas. Claudius himself implemented policies to alleviate the effects of food shortages, such as distributing free or subsidized grain to the population of Rome.
It's worth noting that historical records from that time are incomplete, and some events may have been lost or not adequately documented. However, there is no widespread famine associated with Claudius that is widely recognized by historians.